Welcome

(Contact Info: larry at larryblakeley.com)

Important Note: You will need to click this icon to download the free needed to view most of the images on this Web site - just a couple of clicks and you're "good to go." For reasons why - go here.

A listing and access link to all:
song lyrics and mp3 audio files http://www.royblakeley.name/larry_blakeley/songs/ (all of which are a part of this Web site) can be accessed simply by selecting the "htm" file for the song you want;

poetry http://www.royblakeley.name/larry_blakeley/poetry.htm;

quotations http://www.royblakeley.name/larry_blakeley/quotations.htm; and

essays written by Larry Blakeley http://www.royblakeley.name/larry_blakeley/articles/articles_larry_blakeley.htm,

all of which are used to tell the story in this Web site, can be accessed by going to each respective link set out above.

My son, Larry Blakeley http://www.royblakeley.name/larry_blakeley/larryblakeley_photos_jpeg.htm manages this Web site and the following Web sites:

Larry Blakeley (Contact Info: larry at larryblakeley.com)

Leslie (Blakeley) Adkins - my granddaughter

Lori Ann Blakeley (June 20, 1985 - May 4, 2005) - my granddaughter

Evan Blakeley- my grandson

Major Roy James Blakeley (December 10, 1928 - July 22, 1965) - USAF (KIA)

When I was young my dad would say
Come on son let's go out and play

No matter how hard I try
No matter how many tears I cry
No matter how many years go by
I still can't say goodbye

- "I Still Can't Say Goodbye," Performer: Chet Atkins

MP3 audio file/lyrics http://www.royblakeley.name/larry_blakeley/songs/still_cant_say_goodbye.htm

For a larger image click on the photograph.

Dana-Farber researchers are harnessing programmed cell death, or apoptosis, to attack tumors.

There comes a time in every cell's life to die for the body's greater good. When the orders do come – from outside the cell or within it – the cell obediently destroys itself, and the body disposes of the corpse without a trace.

Though some have called it "suicide without grief," the process of apoptosis, or "programmed cell death," is neither quick nor gentle. Over 24 to 48 hours, a poison cocktail released from within the cell chops up its DNA; the cell shrinks, is dismembered into neatly wrapped pieces, and – after posting a chemical "Eat Me" sign on its surface – is devoured by hungry immune system cells.

Apoptosis rids the body of 50 to 70 billion unwanted cells a day, including worn-out or obsolete cells and those with DNA damage that are prone to running amok and causing cancer. When a cell senses that its genetic blueprint has been damaged – by random events, radiation, or chemicals, for example – it turns on a "death program" of apoptotic events to cull itself from the body.

But this defensive purging can hit a snag, as Dana- Farber's Stanley Korsmeyer, MD, famously discovered about 15 years ago. If a surge of "survival" signals within a damaged cell outweighs its death signals, the cell may escape apoptosis and become the seed of a tumor. Genetic mutations in a cell's DNA, among other events, can turn on an excess of survival signals – just one more way in which cancer exploits natural processes to do its dirty work.

- "Making Cancer Cells Die ‘A Good Death’," Richard Saltus, Paths of Progress http://www.dfci.harvard.edu/abo/news/publications/pop/, Spring/Summer 2005 http://www.dfci.harvard.edu/abo/news/press/apoptosis.pdf

Directory: http://www.royblakeley.name/larry_blakeley/articles/monthly_articles/

File Name: richard_saltus_apoptosis200504.pdf

Post Date: April 17, 2005 at 10:00 AM CDT; 1500 GMT

Stanley J. Korsmeyer, MD http://www.dfci.harvard.edu/abo/news/press/korsmeyer-links.asp, a scientific leader at Dana-Farber Cancer Institute http://www.dfci.harvard.edu/, will be remembered at the Institute as much for his sunny, upbeat disposition and for the way he selflessly helped guide the careers of those who worked for him as he will for his landmark discoveries in the field of cancer research. Dr. Korsmeyer, a non-smoker, died on March 31, 2005, of lung cancer.